Timing of integration into the chromosome is critical for the fitness of an integrative and conjugative element and its bacterial host.

Integrative and conjugative elements (ICEs) are major contributors to genome plasticity in bacteria. ICEs reside integrated in the chromosome of a host bacterium and are passively propagated during chromosome replication and cell division. When activated, ICEs excise from the chromosome and may be t...

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Bibliographic Details
Main Authors: Saria A McKeithen-Mead, Alan D Grossman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010524