Hydrophobic Gating of Ion Permeation in Magnesium Channel CorA.

Ion channels catalyze ionic permeation across membranes via water-filled pores. To understand how changes in intracellular magnesium concentration regulate the influx of Mg2+ into cells, we examine early events in the relaxation of Mg2+ channel CorA toward its open state using massively-repeated mol...

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Bibliographic Details
Main Authors: Chris Neale, Nilmadhab Chakrabarti, Pawel Pomorski, Emil F Pai, Régis Pomès
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4504495?pdf=render