Design, synthesis, and biological evaluation of phenyl-isoxazole-carboxamide derivatives as anticancer agents

The present study aimed to design and synthesize a series of phenyl-isoxazole-carboxamide derivatives and investigate their antitumor and antioxidant activities. The in vitro cytotoxic evaluation was conducted using the MTS assay against four cancer cell lines: hepatocellular carcinoma (Hep3B and He...

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Bibliographic Details
Main Authors: Hawash Mohammed, Jaradat Nidal, Bawwab Noor, Salem Kamilah, Arafat Hadeel, Hajyousef Yousef, Shtayeh Tahrir, Sobuh Shorooq
Format: Article
Language:English
Published: De Gruyter 2021-12-01
Series:Heterocyclic Communications
Subjects:
Online Access:https://doi.org/10.1515/hc-2020-0134