Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis

Involvement of Ca2+ Activated Cl- Channel Ano6 in Platelet Activation and Apoptosis

Background/Aims: The ubiquitously expressed Ca2+ Activated Cl- Channel Ano6 participates in the stimulation of cell membrane scrambling. Defective Ano6 underlies the Scott syndrome, an inherited bleeding disorder with impaired scrambling of plasma membrane phospholipids. At least in theory, the blee...

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Bibliographic Details
Main Authors: Guoxing Liu, Guilai Liu, Hong Chen, Oliver Borst, Meinrad Gawaz, Andrea Vortkamp, Rainer Schreiber, Karl Kunzelmann, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Integrin
Cell volume
Cytosolic Ca2+ concentration
P-selectin
Phosphatidylserine translocation
Online Access:http://www.karger.com/Article/FullText/438554

Internet

http://www.karger.com/Article/FullText/438554

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