Personalization of Aspirin Therapy Ex Vivo in Patients with Atherosclerosis Using Light Transmission Aggregometry

Personalization of Aspirin Therapy Ex Vivo in Patients with Atherosclerosis Using Light Transmission Aggregometry

Acetylsalicylic acid (ASA), also known as aspirin, appears to be ineffective in inhibiting platelet aggregation in 20–30% of patients. Light transmission aggregometry (LTA) is a gold standard platelet function assay. In this pilot study, we used LTA to personalize ASA therapy ex vivo in atherosclero...

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Bibliographic Details
Main Authors: Hamzah Khan, Reid C. Gallant, Abdelrahman Zamzam, Shubha Jain, Sherri Afxentiou, Muzammil Syed, Zachary Kroezen, Meera Shanmuganathan, Philip Britz-McKibbin, Margaret L. Rand, Heyu Ni, Mohammed Al-Omran, Mohammad Qadura
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Diagnostics
Subjects:
aspirin
light transmission aggregometry
non-sensitivity
personalized medicine
atherosclerosis
anti-platelet
Online Access:https://www.mdpi.com/2075-4418/10/11/871

Internet

https://www.mdpi.com/2075-4418/10/11/871

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