The AhR agonist VAF347 augments retinoic acid‐induced differentiation in leukemia cells

In binary cell‐fate decisions, driving one lineage and suppressing the other are conjoined. We have previously reported that aryl hydrocarbon receptor (AhR) promotes retinoic acid (RA)‐induced granulocytic differentiation of lineage bipotent HL‐60 myeloblastic leukemia cells. VAF347, an AhR agonist,...

Full description

Bibliographic Details
Main Authors: Christopher N. Ibabao, Rodica P. Bunaciu, Deanna M.W. Schaefer, Andrew Yen
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1016/j.fob.2015.04.002