Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer’s Disease

Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer’s Disease

Glial fibrillary acidic protein (GFAP) is an intermediate filament structural protein involved in cytoskeleton assembly and integrity, expressed in high abundance in activated glial cells. GFAP is neuroprotective, as knockout mice are hypersensitive to traumatic brain injury. GFAP in cerebrospinal f...

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Bibliographic Details
Main Authors: Akshatha Ganne, Meenakshisundaram Balasubramaniam, W. Sue T. Griffin, Robert J. Shmookler Reis, Srinivas Ayyadevara
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
glial fibrillary acidic protein (GFAP)
protein aggregation
protein phosphorylation
post-translational modification (of proteins)
Alzheimer’s disease (AD)
biomarkers
Online Access:https://www.mdpi.com/1999-4923/14/7/1354

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https://www.mdpi.com/1999-4923/14/7/1354

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