RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis

Abstract RNA-binding proteins (RBPs) play important roles in cancer development and treatment. However, the tumor-promoting RBPs and their partners, which may potentially serve as the cancer therapeutic targets, need to be further identified. Here, we report that zinc finger CCHC domain-containing p...

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Bibliographic Details
Main Authors: Ha Zhu, Kun Chen, Yali Chen, Juan Liu, Xiaomin Zhang, Yumei Zhou, Qiuyan Liu, Bingjing Wang, Taoyong Chen, Xuetao Cao
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-01033-8