Does the VDR gene polymorphism influence the efficacy of denosumab therapy in postmenopausal osteoporosis?

Does the VDR gene polymorphism influence the efficacy of denosumab therapy in postmenopausal osteoporosis?

IntroductionOne of the challenges of personalized medicine is a departure from traditional pharmacology toward individualized, genotype-based therapies. Postmenopausal osteoporosis is a prevalent condition requiring intensive treatment, whose effects are measurable only after a long time, and the go...

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Bibliographic Details
Main Authors: Anna Wawrzyniak, Marzena Skrzypczak-Zielińska, Michał Michalak, Marta Kaczmarek-Ryś, Alicja Ewa Ratajczak, Anna Maria Rychter, Kinga Skoracka, Michalina Marcinkowska, Ryszard Słomski, Agnieszka Dobrowolska, Iwona Krela-Kaźmierczak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
VDR gene polymorphism
denosumab therapy
postmenopausal osteoporosis
bone fracture
osteoporosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1063762/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1063762/full

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