Successful xenotransplantation of testicular cells following fractionated chemotherapy of recipient birds

Abstract An essential step in the success of germ cell transplantation is the preparation of the recipient’s testicular environment to increase the availability of stem cell niches. However, most methods for this purpose in birds face serious limitations such as partial germ cell depletion, high tox...

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Bibliographic Details
Main Authors: Marcel Henrique Blank, Allison Jun Taguchi Kawaoku, Bruno Rogério Rui, Ana Claudia Oliveira Carreira, Thais Rose dos Santos Hamilton, Marcelo Demarchi Goissis, Ricardo José Garcia Pereira
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45019-0