Causal association between genetically predicted circulating immune cell counts and frailty: a two-sample Mendelian randomization study

Causal association between genetically predicted circulating immune cell counts and frailty: a two-sample Mendelian randomization study

BackgroundDespite the recognized link between immune responses and frailty, the association between immune cell counts and frailty based on previous observational studies remains disputed, with uncertain causal nexus. This study aimed to elucidate causal association between genetically predicted cir...

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Bibliographic Details
Main Authors: Xiao-Guang Guo, Ya-Juan Zhang, Ya-Xin Lu, Jia-Mei Lu, Jie Zhang, Hui-Xin Li, Chao-Jin Chen, Jian-Jun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
immune cell
inflammation
frailty index
Mendelian randomization
eosinophil count
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1336498/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1336498/full

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