Sustained IP3-linked Ca2+ signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism

Sustained IP3-linked Ca2+ signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism

Rewiring of mitochondrial metabolism has been described in different cancers as a key step for their progression. Calcium (Ca2+) signaling regulates mitochondrial function and is known to be altered in several malignancies, including triple negative breast cancer (TNBC). However, whether and how the...

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Bibliographic Details
Main Authors: Riccardo Filadi, Agnese De Mario, Matteo Audano, Patrizia Romani, Silvia Pedretti, Cesar Cardenas, Sirio Dupont, Cristina Mammucari, Nico Mitro, Paola Pizzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
IP3
Ca2+
breast cancer
TNBC
mitochondria
MCU
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1071037/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1071037/full

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