Litter expansion alters metabolic homeostasis in a sex specific manner.

Nutritional manipulations early in life have been shown to influence growth rate and elicit long lasting effects which in turn has been found to impact lifespan. Therefore, we studied the long-term effects of pre-weaning dietary restriction implemented by litter expansion (4, 6, 8, 10, and 12 pups p...

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Bibliographic Details
Main Authors: Kavitha Kurup, Shivani N Mann, Jordan Jackson, Stephanie Matyi, Michelle Ranjo-Bishop, Willard M Freeman, Michael B Stout, Arlan Richardson, Archana Unnikrishnan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237199