Electrospun Amorphous Solid Dispersions with Lopinavir and Ritonavir for Improved Solubility and Dissolution Rate

Electrospun Amorphous Solid Dispersions with Lopinavir and Ritonavir for Improved Solubility and Dissolution Rate

Lopinavir (LPV) and ritonavir (RTV) are two of the essential antiretroviral active pharmaceutical ingredients (APIs) characterized by poor solubility. Hence, attempts have been made to improve both their solubility and dissolution rate. One of the most effective approaches used for this purpose is t...

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Bibliographic Details
Main Authors: Ewelina Łyszczarz, Oskar Sosna, Justyna Srebro, Aleksandra Rezka, Dorota Majda, Aleksander Mendyk
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Nanomaterials
Subjects:
lopinavir
ritonavir
poorly soluble drug
electrospinning
amorphous solid dispersion
dissolution enhancement
Online Access:https://www.mdpi.com/2079-4991/14/19/1569

Internet

https://www.mdpi.com/2079-4991/14/19/1569

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