High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis

High producer variant of lipoprotein lipase may protect from hepatocellular carcinoma in alcohol-associated cirrhosis

Background & Aims: Progression of alcohol-associated liver disease (ALD) is driven by genetic predisposition. The rs13702 variant in the lipoprotein lipase (LPL) gene is linked to non-alcoholic fatty liver disease. We aimed at clarifying its role in ALD. Methods: Patients with alcohol-associ...

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Bibliographic Details
Main Authors: Franziska Schmalz, Janett Fischer, Hamish Innes, Stephan Buch, Christine Möller, Madlen Matz-Soja, Witigo von Schönfels, Benjamin Krämer, Bettina Langhans, Alexandra Klüners, Michael Soyka, Felix Stickel, Jacob Nattermann, Christian P. Strassburg, Thomas Berg, Philipp Lutz, Hans Dieter Nischalke
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:JHEP Reports
Subjects:
Cirrhosis
Alcohol-associated liver disease
HCC
LPL
rs13702
rs328
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923000150

Internet

http://www.sciencedirect.com/science/article/pii/S2589555923000150

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