Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis

Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis

Telomere shortening can be enhanced upon human immunodeficiency virus (HIV) infection and by antiretroviral (ARV) exposures. The aim of this study was to evaluate the acute and long-term effect on telomere shortening of two ARV prophylaxes, lopinavir/ritonavir (LPV/r) and lamivudine (3TC), administe...

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Bibliographic Details
Main Authors: Audrey Monnin, Amélie Vizeneux, Nicolas Nagot, Sabrina Eymard-Duvernay, Nicolas Meda, Mandisa Singata-Madliki, Grace Ndeezi, James Kashugyera Tumwine, Chipepo Kankasa, Ameena Goga, Thorkild Tylleskär, Philippe Van de Perre, Jean-Pierre Molès
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Children
Subjects:
HIV
children
prophylaxis
telomere shortening
growth
neuropsychological development
Online Access:https://www.mdpi.com/2227-9067/8/9/796

Internet

https://www.mdpi.com/2227-9067/8/9/796

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