Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23ahl

Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23ahl

Summary: Mouse studies continue to help elaborate upon the genetic landscape of mammalian disease and the underlying molecular mechanisms. Here, we have investigated an Embigintm1b allele maintained on a standard C57BL/6N background and on a co-isogenic C57BL/6N background in which the Cdh23ahl alle...

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Bibliographic Details
Main Authors: Sherylanne Newton, Carlos Aguilar, Rosie K. Bunton-Stasyshyn, Marisa Flook, Michelle Stewart, Walter Marcotti, Steve Brown, Michael R. Bowl
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Neurogenetics
Developmental genetics
Phenotyping
Model organism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223021338

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http://www.sciencedirect.com/science/article/pii/S2589004223021338

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