Amyloid Beta Pathology Exacerbates Weight Loss and Brain Cytokine Responses following Low-Dose Lipopolysaccharide in Aged Female Tg2576 Mice

Amyloid Beta Pathology Exacerbates Weight Loss and Brain Cytokine Responses following Low-Dose Lipopolysaccharide in Aged Female Tg2576 Mice

Systemic inflammation has been implicated in the progression of Alzheimer’s disease (AD); however, less is understood about how existing AD pathology contributes to adverse outcomes following acute inflammatory insults. In the present study, our goal was to determine how AD-associated amyloid beta (...

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Bibliographic Details
Main Authors: Rachel C. Knopp, Kristen K. Baumann, Miranda L. Wilson, William A. Banks, Michelle A. Erickson
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
inflammation
Alzheimer’s disease
amyloid beta
serum amyloid A
sickness behavior
depressive-like behavior
Online Access:https://www.mdpi.com/1422-0067/23/4/2377

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https://www.mdpi.com/1422-0067/23/4/2377

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