p53 biology and reactivation for improved therapy in MDS and AML

Abstract Myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) originate from preleukemic hematopoietic conditions, such as clonal hematopoiesis of indeterminate potential (CHIP) or clonal cytopenia of undetermined significance (CCUS) and have variable outcomes despite the successful imple...

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Bibliographic Details
Main Author: Joanna E. Zawacka
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-024-00579-9