Two cases of successful sirolimus treatment for patients with activated phosphoinositide 3-kinase δ syndrome 1

Two cases of successful sirolimus treatment for patients with activated phosphoinositide 3-kinase δ syndrome 1

Abstract Background Activated phosphoinositide3-kinase (PI3K) δ syndrome 1 (APDS1) is a novel inborn errors of immunity (IEIs) caused by heterozygous gain of function mutations in PI3Kδ catalytic p110δ (PIK3CD). APDS1 has a spectrum of clinical manifestations. Recurrent respiratory infections, lymph...

Full description

Bibliographic Details
Main Authors: Lu Jiang, Xiaohan Hu, Qiang Lin, Ruyue Chen, Yunyan Shen, Yun Zhu, Qinying Xu, Xiaozhong Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Activated PI3Kδ syndrome
PIK3CD
Genetic variant
Sirolimus
Online Access:https://doi.org/10.1186/s13223-023-00840-0

Internet

https://doi.org/10.1186/s13223-023-00840-0

Similar Items