Genome-Wide Requirements for Resistance to Functionally Distinct DNA-Damaging Agents.
The mechanistic and therapeutic differences in the cellular response to DNA-damaging compounds are not completely understood, despite intense study. To expand our knowledge of DNA damage, we assayed the effects of 12 closely related DNA-damaging agents on the complete pool of ~4,700 barcoded homozyg...
| Format: | Article |
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| Language: | English |
| Published: |
Public Library of Science (PLoS)
2005-08-01
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| Series: | PLoS Genetics |
| Online Access: | http://dx.doi.org/10.1371/journal.pgen.0010024 |