Antioxidant evaluation and computational prediction of prospective drug-like compounds from polyphenolic-rich extract of Hibiscus cannabinus L. seed as antidiabetic and neuroprotective targets: assessment through in vitro and in silico studies

Antioxidant evaluation and computational prediction of prospective drug-like compounds from polyphenolic-rich extract of Hibiscus cannabinus L. seed as antidiabetic and neuroprotective targets: assessment through in vitro and in silico studies

Abstract Background Reports have implicated diabetes mellitus (DM) and Alzheimer’s disease (AD) as some of the global persistent health challenges with no lasting solutions, despite of significant inputs of modern-day pharmaceutical firms. This study therefore, aimed to appraise the in vitro antioxi...

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Bibliographic Details
Main Authors: Olakunle Bamikole Afolabi, Oluwaseun Ruth Olasehinde, Damilola Grace Olanipon, Samson Olatunde Mabayoje, Olufemi Michael Familua, Kikelomo Folake Jaiyesimi, Esther Kemi Agboola, Tolulope Olajumoke Idowu, Olabisi Tajudeen Obafemi, Oyindamola Adeniyi Olaoye, Omotade Ibidun Oloyede
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Hibiscus cannabinus seed
Antidiabetic agent
Neurodegenerative conditions
MM-GBSA scores
Molecular docking
Online Access:https://doi.org/10.1186/s12906-023-04023-7

Internet

https://doi.org/10.1186/s12906-023-04023-7

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