PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells

PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells

Prime editing is a recently developed CRISPR/Cas9 based gene engineering tool that allows the introduction of short insertions, deletions, and substitutions into the genome. However, the efficiency of prime editing, which typically achieves editing rates of around 10%–30%, has not matched its versat...

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Bibliographic Details
Main Authors: Dorottya Anna Simon, András Tálas, Péter István Kulcsár, Zsuzsanna Biczók, Sarah Laura Krausz, György Várady, Ervin Welker
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-02-01
Series:eLife
Subjects:
CRISPR
Cas9
prime editing
fluorescent
fluorescent reporter
reporter
Online Access:https://elifesciences.org/articles/69504

Internet

https://elifesciences.org/articles/69504

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