Molecular mechanism study of HGF/c-MET pathway activation and immune regulation for a tumor diagnosis model

Molecular mechanism study of HGF/c-MET pathway activation and immune regulation for a tumor diagnosis model

Abstract Background Hepatocyte growth factor (HGF) binds to the c-mesenchymal-epithelial transition (C-MET) receptor and activates downstream signaling pathways, playing an essential role in the development of various cancers. Given the role of this signaling pathway, the primary therapeutic directi...

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Bibliographic Details
Main Authors: Zhibo Shen, Wenhua Xue, Yuanyuan Zheng, Qishun Geng, Le Wang, Zhirui Fan, Wenbin Wang, Ying Yue, Yunkai Zhai, Lifeng Li, Jie Zhao
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cancer Cell International
Subjects:
HGF
c-MET
RNAseq
Immune cells
Pathway score
Immune infiltration
Online Access:https://doi.org/10.1186/s12935-021-02051-2

Internet

https://doi.org/10.1186/s12935-021-02051-2

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