Methylenetetrahydrofolate reductase polymorphic variants C677T and A1298C in rectal cancer in Slavic population: significance for cancer risk and response to chemoradiotherapy

Methylenetetrahydrofolate reductase polymorphic variants C677T and A1298C in rectal cancer in Slavic population: significance for cancer risk and response to chemoradiotherapy

Background: Methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNPs) have been suggested as risk, prognostic, and predictive factors for colorectal cancer in various populations, but have not been validated so far. The aim of this study was to examine the association of MTH...

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Bibliographic Details
Main Authors: Aleksandra Stanojevic, Jelena Spasic, Mladen Marinkovic, Suzana Stojanovic-Rundic, Radmila Jankovic, Ana Djuric, Jerome Zoidakis, Remond J. A. Fijneman, Sergi Castellvi-Bel, Milena Cavic
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Genetics
Subjects:
chemoradiotherapy
methylenetetrahydrofolate reductase
MTHFR C677T
MTHFR A1298C
rectal cancer
single nucleotide polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1299599/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1299599/full

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