Combined in vivo MRI assessment of locus coeruleus and nucleus basalis of Meynert integrity in amnestic Alzheimer’s disease, suspected-LATE and frontotemporal dementia

Abstract Background The locus coeruleus (LC) and the nucleus basalis of Meynert (NBM) are altered in early stages of Alzheimer’s disease (AD). Little is known about LC and NBM alteration in limbic-predominant age-related TDP-43 encephalopathy (LATE) and frontotemporal dementia (FTD). The aim of the...

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Main Authors: Julien Lagarde, Pauline Olivieri, Matteo Tonietto, Camille Noiray, Stéphane Lehericy, Romain Valabrègue, Fabien Caillé, Philippe Gervais, Martin Moussion, Michel Bottlaender, Marie Sarazin
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Alzheimer’s Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13195-024-01466-z