The ability to generate senescent progeny as a mechanism underlying breast cancer cell heterogeneity.

The ability to generate senescent progeny as a mechanism underlying breast cancer cell heterogeneity.

BACKGROUND: Breast cancer is a remarkably heterogeneous disease. Luminal, basal-like, "normal-like", and ERBB2+ subgroups were identified and were shown to have different prognoses. The mechanisms underlying this heterogeneity are poorly understood. In our study, we explored the role of ce...

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Main Authors: Mine Mumcuoglu, Sevgi Bagislar, Haluk Yuzugullu, Hani Alotaibi, Serif Senturk, Pelin Telkoparan, Bala Gur-Dedeoglu, Burcu Cingoz, Betul Bozkurt, Uygar H Tazebay, Isik G Yulug, K Can Akcali, Mehmet Ozturk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2891998?pdf=render

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http://europepmc.org/articles/PMC2891998?pdf=render

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