Microarchitectural mimicking of stroma-induced vasculature compression in pancreatic tumors using a 3D engineered model
Fibrotic tumors, such as pancreatic ductal adenocarcinoma (PDAC), are characterized for high desmoplastic reaction, which results in high intra-tumoral solid stress leading to the compression of blood vessels. These microarchitectural alterations cause loss of blood flow and poor intra-tumoral deliv...
| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
KeAi Communications Co., Ltd.
2023-04-01
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| coleção: | Bioactive Materials |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2452199X2200411X |