Prolonged Subcutaneous Administration of Oxytocin Accelerates Angiotensin II-Induced Hypertension and Renal Damage in Male Rats.

Prolonged Subcutaneous Administration of Oxytocin Accelerates Angiotensin II-Induced Hypertension and Renal Damage in Male Rats.

Oxytocin and its receptor are synthesised in the heart and blood vessels but effects of chronic activation of this peripheral oxytocinergic system on cardiovascular function are not known. In acute studies, systemic administration of low dose oxytocin exerted a protective, preconditioning effect in...

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Bibliographic Details
Main Authors: James Phie, Nagaraja Haleagrahara, Patricia Newton, Constantin Constantinoiu, Zoltan Sarnyai, Lisa Chilton, Robert Kinobe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4579129?pdf=render

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http://europepmc.org/articles/PMC4579129?pdf=render

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