CAF01 potentiates immune responses and efficacy of an inactivated influenza vaccine in ferrets.

Trivalent inactivated vaccines (TIV) against influenza are given to 350 million people every year. Most of these are non-adjuvanted vaccines whose immunogenicity and protective efficacy are considered suboptimal. Commercially available non-adjuvanted TIV are known to elicit mainly a humoral immune r...

Full description

Bibliographic Details
Main Authors: Cyril Jean-Marie Martel, Else Marie Agger, Julie Juul Poulsen, Trine Hammer Jensen, Lars Andresen, Dennis Christensen, Lars Peter Nielsen, Merete Blixenkrone-Møller, Peter Andersen, Bent Aasted
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3151275?pdf=render