Immune system changes in the pathogenesis of neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome occurring with a frequency of 1: 3000 of the population. NF1 is caused by germline heterozygous mutations in the NF1 gene, which encodes the oncosuppressor neurofibromin. The disease has a specific progressive course with multiple neurofi...

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Bibliographic Details
Main Author: R. N. Mustafin
Format: Article
Language:Russian
Published: ABV-press 2022-01-01
Series:Онкогематология
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/526