Immune system changes in the pathogenesis of neurofibromatosis type 1
Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome occurring with a frequency of 1: 3000 of the population. NF1 is caused by germline heterozygous mutations in the NF1 gene, which encodes the oncosuppressor neurofibromin. The disease has a specific progressive course with multiple neurofi...
Main Author: | |
---|---|
Format: | Article |
Language: | Russian |
Published: |
ABV-press
2022-01-01
|
Series: | Онкогематология |
Subjects: | |
Online Access: | https://oncohematology.abvpress.ru/ongm/article/view/526 |