Selection of human induced pluripotent stem cells lines optimization of cardiomyocytes differentiation in an integrated suspension microcarrier bioreactor

Selection of human induced pluripotent stem cells lines optimization of cardiomyocytes differentiation in an integrated suspension microcarrier bioreactor

Abstract Background The production of large quantities of cardiomyocyte is essential for the needs of cellular therapies. This study describes the selection of a human-induced pluripotent cell (hiPSC) line suitable for production of cardiomyocytes in a fully integrated bioprocess of stem cell expans...

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Bibliographic Details
Main Authors: Filip Laco, Alan Tin-Lun Lam, Tsung-Liang Woo, Gerine Tong, Valerie Ho, Poh-Loong Soong, Elina Grishina, Kun-Han Lin, Shaul Reuveny, Steve Kah-Weng Oh
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Stem Cell Research & Therapy
Subjects:
Bioprocessing
Cardiomyocytes
Human induced pluripotent stem cells
Microcarriers
Stirred tank bioreactor
OptioQUANT™ platform
Online Access:http://link.springer.com/article/10.1186/s13287-020-01618-6

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http://link.springer.com/article/10.1186/s13287-020-01618-6

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