Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports

Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports

IntroductionSince vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these diseases. Two recent case reports have found a potentia...

Full description

Bibliographic Details
Main Authors: Janet Sultana, Giulia Scondotto, Paola Maria Cutroneo, Francesca Morgante, Gianluca Trifirò
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
pharmacovigilance
VigiBase
Alzheimer’s disease
Parkinson’ disease
dementia
neurodegeneration
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00315/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00315/full

Similar Items