Neuroprotective Effects of Thiamine and Precursors with Higher Bioavailability: Focus on Benfotiamine and Dibenzoylthiamine

Neuroprotective Effects of Thiamine and Precursors with Higher Bioavailability: Focus on Benfotiamine and Dibenzoylthiamine

Thiamine (vitamin B1) is essential for brain function because of the coenzyme role of thiamine diphosphate (ThDP) in glucose and energy metabolism. In order to compensate thiamine deficiency, several thiamine precursors with higher bioavailability were developed since the 1950s. Among these, the thi...

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Bibliographic Details
Main Authors: Margaux Sambon, Pierre Wins, Lucien Bettendorff
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
thiamine diphosphate
neurodegeneration
neuroprotection
Alzheimer’s disease
oxidative stress
diabetes
Online Access:https://www.mdpi.com/1422-0067/22/11/5418

Internet

https://www.mdpi.com/1422-0067/22/11/5418

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