Molecular Mechanism of Mesenchyme Homeobox 1 in Transforming Growth Factor β1–Induced P311 Gene Transcription in Fibrosis

Molecular Mechanism of Mesenchyme Homeobox 1 in Transforming Growth Factor β1–Induced P311 Gene Transcription in Fibrosis

Organ fibrosis is characterized by excessive fibroblast, and extracellular matrix and the molecular basis are not fully elucidated. Recent studies have proven that P311, an 8-kDa conserved protein, could promote various organ fibrosis, such as skin, kidney, liver, and lung, partially through upregul...

Full description

Bibliographic Details
Main Authors: Zhiyuan Wei, Chao Han, Haisheng Li, Weifeng He, Junyi Zhou, Hui Dong, Yuzhang Wu, Yi Tian, Gaoxing Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Meox1
P311
promoter
transcription factor
fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00059/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.00059/full

Similar Items