Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial

Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial

Abstract Background Whole sporozoite immunization under chemoprophylaxis (CPS regime) induces long-lasting sterile homologous protection in the controlled human malaria infection model using Plasmodium falciparum strain NF54. The relative proficiency of liver-stage parasite development may be an imp...

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Bibliographic Details
Main Authors: Saskia C. van der Boor, Manon Alkema, Geert-Jan van Gemert, Karina Teelen, Marga van de Vegte-Bolmer, Jona Walk, Reinout van Crevel, Quirijn de Mast, Christian F. Ockenhouse, Robert W. Sauerwein, Matthew B. B. McCall
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Medicine
Subjects:
Malaria
Plasmodium falciparum
Whole sporozoite immunization
Vaccine-induced protection
NF135
Online Access:https://doi.org/10.1186/s12916-023-02788-9

Internet

https://doi.org/10.1186/s12916-023-02788-9

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