Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial
Abstract Background Whole sporozoite immunization under chemoprophylaxis (CPS regime) induces long-lasting sterile homologous protection in the controlled human malaria infection model using Plasmodium falciparum strain NF54. The relative proficiency of liver-stage parasite development may be an imp...
Main Authors: | Saskia C. van der Boor, Manon Alkema, Geert-Jan van Gemert, Karina Teelen, Marga van de Vegte-Bolmer, Jona Walk, Reinout van Crevel, Quirijn de Mast, Christian F. Ockenhouse, Robert W. Sauerwein, Matthew B. B. McCall |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-04-01
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Series: | BMC Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12916-023-02788-9 |
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