A high-resolution view of genome-wide pneumococcal transformation.

Transformation is an important mechanism of microbial evolution through which bacteria have been observed to rapidly adapt in response to clinical interventions; examples include facilitating vaccine evasion and the development of penicillin resistance in the major respiratory pathogen Streptococcus...

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Bibliographic Details
Main Authors: Nicholas J Croucher, Simon R Harris, Lars Barquist, Julian Parkhill, Stephen D Bentley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3375284?pdf=render