FACILE SYNTHESIS, CHARACTERIZATION AND DFT CALCULATIONS OF 2-ACETYL PYRIDINE DERIVATIVES

FACILE SYNTHESIS, CHARACTERIZATION AND DFT CALCULATIONS OF 2-ACETYL PYRIDINE DERIVATIVES

Deprotonation of 2-acetylpyridine was carried out in the presence of NaH as a phase transfer catalyst instead of NaOH to minimize side products formation. The products were then treated with two equivalents of alkyl/aryl halide to synthesize a variety of acetyl pyridine derivatives. The compounds we...

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Bibliographic Details
Main Authors: Haroon ur Rashid, Adnan Shahzad, Zarif Gul, Ezzat Khan, Muhammad Naveed Umar, Muhammad Raza Shah, Awal Noor, Sher Wali Khan
Format: Article
Language:English
Published: Sociedade Brasileira de Química
Series:Química Nova
Subjects:
2-acetylpyridine
phase transfer catalyst
NMR studies
X-ray structure
DFT calculations
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422017000800902&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422017000800902&lng=en&tlng=en

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