Smoking-Associated Exposure of Human Primary Bronchial Epithelial Cells to Aldehydes: Impact on Molecular Mechanisms Controlling Mitochondrial Content and Function

Smoking-Associated Exposure of Human Primary Bronchial Epithelial Cells to Aldehydes: Impact on Molecular Mechanisms Controlling Mitochondrial Content and Function

Chronic obstructive pulmonary disease (COPD) is a devastating lung disease primarily caused by exposure to cigarette smoke (CS). During the pyrolysis and combustion of tobacco, reactive aldehydes such as acetaldehyde, acrolein, and formaldehyde are formed, which are known to be involved in respirato...

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Bibliographic Details
Main Authors: Christy B. M. Tulen, Evert Duistermaat, Johannes W. J. M. Cremers, Walther N. M. Klerx, Paul H. B. Fokkens, Naömi Weibolt, Nico Kloosterboer, Mieke A. Dentener, Eric R. Gremmer, Phyllis J. J. Jessen, Evi J. C. Koene, Lou Maas, Antoon Opperhuizen, Frederik-Jan van Schooten, Yvonne C. M. Staal, Alexander H. V. Remels
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
acetaldehyde
acrolein
formaldehyde
cigarette smoke
primary bronchial epithelial cells
mitochondria
Online Access:https://www.mdpi.com/2073-4409/11/21/3481

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https://www.mdpi.com/2073-4409/11/21/3481

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