Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques

Abstract Despite the availability of several effective SARS-CoV-2 vaccines, additional vaccines will be required for optimal global vaccination. In this study, we investigate the immunogenicity and protective efficacy of the GBP510 protein subunit vaccine adjuvanted with AS03, which has recently bee...

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Bibliographic Details
Main Authors: Catherine Jacob-Dolan, Jingyou Yu, Katherine McMahan, Victoria Giffin, Abishek Chandrashekar, Amanda J. Martinot, Tochi Anioke, Olivia C. Powers, Kevin Hall, David Hope, Jessica Miller, Nichole P. Hachmann, Benjamin Chung, Sarah Gardner, Daniel Sellers, Julia Barrett, Mark G. Lewis, Hanne Andersen, Harry Kleanthous, Ki-Woen Seo, Su Jeen Lee, Yong Wook Park, Hun Kim, Dan H. Barouch
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00622-0