Mechanoelectrical feedback in pulmonary vein arrhythmogenesis: Clinical challenges and therapeutic opportunities

Abstract Mechanoelectrical feedback is an important factor in the pathophysiology of atrial fibrillation (AF). Ectopic electrical activity originating from pulmonary vein (PV) myocardial sleeves has been found to trigger and maintain paroxysmal AF. Dilated PVs by high stretching force may activate m...

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Bibliographic Details
Main Authors: Yen‐Yu Lu, Yao‐Chang Chen, Yung‐Kuo Lin, Shih‐Ann Chen, Yi‐Jen Chen
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Journal of Arrhythmia
Subjects:
Online Access:https://doi.org/10.1002/joa3.12391