Synthesis and Characterization of Dimeric Artesunate Glycerol Monocaprylate Conjugate and Formulation of Nanoemulsion Preconcentrate

Malaria is one of the major life-threatening health problems worldwide. Artesunate is the most potent antimalarial drug to combat severe malaria. However, development of drug resistance, short plasma half-life, and poor bioavailability limit the efficacy of this drug. Here, we applied the dimerizati...

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Bibliographic Details
Main Authors: Rana Hore, Nazmul Hasan, Karsten Mäder, Jörg Kressler
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/13/5208