Endogenous Biomarkers for SLC Transporter-Mediated Drug-Drug Interaction Evaluation

Endogenous Biomarkers for SLC Transporter-Mediated Drug-Drug Interaction Evaluation

Membrane transporters play an important role in the absorption, distribution, metabolism, and excretion of xenobiotic substrates, as well as endogenous compounds. The evaluation of transporter-mediated drug-drug interactions (DDIs) is an important consideration during the drug development process an...

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Bibliographic Details
Main Authors: Yang Li, Zahra Talebi, Xihui Chen, Alex Sparreboom, Shuiying Hu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
membrane transporters
endogenous biomarkers
drug-drug interactions
drug development
Online Access:https://www.mdpi.com/1420-3049/26/18/5500

Internet

https://www.mdpi.com/1420-3049/26/18/5500

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