Comparison of SARS-CoV-2 spike RNA sequences in feces and nasopharynx indicates intestinal replication

Comparison of SARS-CoV-2 spike RNA sequences in feces and nasopharynx indicates intestinal replication

Abstract Background Little is known of possible selection and replication of SARS-CoV-2 in the intestines and if viral load in feces is associated with severity of disease. Therefore, sequence variations of the spike region in strains collected from feces and nasopharynx (NPH) from the same patients...

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Bibliographic Details
Main Authors: Thomas Beck-Friis, Ambjörn Kärmander, Kristina Nyström, Hao Wang, Magnus Gisslén, Lars-Magnus Andersson, Heléne Norder
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Gut Pathogens
Subjects:
SARS-CoV-2
COVID-19
Gastrointestinal tract
Feces
Genomic structural variation
Mutation
Online Access:https://doi.org/10.1186/s13099-022-00509-w

Internet

https://doi.org/10.1186/s13099-022-00509-w

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