Tat-CIAPIN1 Prevents Pancreatic β-Cell Death in hIAPP-Induced RINm5F Cells and T2DM Animal Model

Tat-CIAPIN1 Prevents Pancreatic β-Cell Death in hIAPP-Induced RINm5F Cells and T2DM Animal Model

It is well known that the cytokine-induced apoptosis inhibitor 1 (CIAPIN1) protein plays an important role in biological progresses as an anti-apoptotic protein. Human islet amyloid peptide (hIAPP), known as amylin, is caused to pancreatic β-cell death in type 2 diabetes mellitus (T2DM). However, th...

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Bibliographic Details
Main Authors: Hyeon Ji Yeo, Min Jea Shin, Ki-Yeon Yoo, Bo Hyun Jung, Won Sik Eum, Soo Young Choi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
Tat-CIAPIN1
T2DM
IAPP
MAPK
protein therapy
Online Access:https://www.mdpi.com/1422-0067/24/13/10478

Internet

https://www.mdpi.com/1422-0067/24/13/10478

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