Maternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation

Maternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation

The placental inflammatory processes induced maternally result in preterm birth (PTB). Serum amyloid A (SAA) is a well-known biomarker of inflammation. The objective of this study was to investigate whether murine placental SAA isoforms (SAA1–4) participate in the mechanism of spontaneous PTB and wh...

Full description

Bibliographic Details
Main Authors: Yang Liu, Jin Liu, Anguo Liu, Hillary Yin, Irina Burd, Jun Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
preterm birth
intrauterine inflammation
serum amyloid A (SAA)
placenta
siRNA treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.902096/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.902096/full

Similar Items