Osteogenically committed hUCMSCs-derived exosomes promote the recovery of critical-sized bone defects with enhanced osteogenic properties

Osteogenically committed hUCMSCs-derived exosomes promote the recovery of critical-sized bone defects with enhanced osteogenic properties

Low viability of seed cells and the concern about biosafety restrict the application of cell-based tissue-engineered bone (TEB). Exosomes that bear similar bioactivities to donor cells display strong stability and low immunogenicity. Human umbilical cord mesenchymal stem cells-derived exosomes (hUCM...

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Bibliographic Details
Main Authors: Shuyi Li, Qiong Rong, Yang Zhou, Yuejuan Che, Ziming Ye, Junfang Liu, Jinheng Wang, Miao Zhou
Format: Article
Language:English
Published: AIP Publishing LLC 2024-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0159740

Internet

http://dx.doi.org/10.1063/5.0159740

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