Protective Role of Toll-like Receptor 3-Induced Type I Interferon in Murine Coronavirus Infection of Macrophages

Protective Role of Toll-like Receptor 3-Induced Type I Interferon in Murine Coronavirus Infection of Macrophages

Toll-like Receptors (TLRs) sense viral infections and induce production of type I interferons (IFNs), other cytokines, and chemokines. Viral recognition by TLRs and other pattern recognition receptors (PRRs) has been proven to be cell-type specific. Triggering of TLRs with selected ligands can be be...

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Bibliographic Details
Main Authors: Sonia Navas-Martin, Nneka Ikpeze, Julio Martin-Garcia, Liudmila Mazaleuskaya, Rogier Veltrop
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Viruses
Subjects:
murine coronavirus
macrophage
TLR
poly I:C
type I IFN
antiviral state
Online Access:http://www.mdpi.com/1999-4915/4/5/901

Internet

http://www.mdpi.com/1999-4915/4/5/901

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