Longevity and Mechanism of Heterosubtypic Protection Induced by M2SR (M2-Deficient Single-Replication) Live Influenza Virus Vaccine in Mice

Longevity and Mechanism of Heterosubtypic Protection Induced by M2SR (M2-Deficient Single-Replication) Live Influenza Virus Vaccine in Mice

Seasonal influenza and the threat of global pandemics present a continuing threat to public health. However, conventional inactivated influenza vaccines (IAVs) provide little cross-protective immunity and suboptimal efficacy, even against well-matched strains. Furthermore, the protection against mat...

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Bibliographic Details
Main Authors: Sally Sarawar, Claudia R. Gabaglia, Adriana Sanchez, Yasuko Hatta, Peter Dias, Gabriele Neumann, Yoshihiro Kawaoka, Pamuk Bilsel
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Vaccines
Subjects:
influenza
vaccine
duration
antibody
heterosubtypic
depletion
Online Access:https://www.mdpi.com/2076-393X/10/12/2131

Internet

https://www.mdpi.com/2076-393X/10/12/2131

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